SingleB® Hybridoma Protein Expression

Bispecific Antibody Expression

Bispecific antibody (BsAb) is a special antibody that can bind two different antigens or different epitopes of an antigen at the same time, and can mediate the mechanism that many monoclonal antibodies cannot achieve. The research of bispecific antibodies is of great significance for the immunotherapy of cancer. Currently, six bispecific antibody drugs have been approved to market all over the world.

DetaiBio has rich experience in the field of bispecific antibody customization. We are able to provide you with the expression and purification of various forms of bispecific antibodies.

Service Features

Multiple Types

Multiple types of bispecific antibodies can be expressed

Highly Efficient

3 weeks at the fatest from gene synthesis to purification

High Throughput

The monthly throughput can reach 1000 orders

Highly Experienced

10 years of antibody expression experience
Annual delivery of more than 1000

Structures of Bispecific Antibodies

  • Bispecific antibodies with Fc region
  • Bispecific antibodies without Fc region


Gene Synthesis (optional)

1 week

  • Codon optimization
  • Gene synthesis


~1 week

  • Vector construction
  • Sequencing validation
  • Plasmid extraction

Expression & Purification

~2 weeks

  • Cell transfection
  • Antibody expression

& Deliverables

3 days

  • Purified Antibodies
  • Cloning vector
  • CoA

Case Study

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