BSA is a protein commonly used as a standard in various biochemical applications, including enzyme assays, protein quantification, and electrophoresis. BSA is also used in cell culture media, diagnostic tests, and as a stabilizing agent for biomolecules.

Eribulin is a cell microtubule dynamics inhibitor and a soft sponge like anti-tumor drug. ADC loaded with Eribulin has a strong bystander effect and good clinical efficacy. Due to the release of payload after ADC administration, there is an increase in unbound payload and changes in ADC composition (i.e. DAR distribution). In order to address the challenges and difficulties in ADC drug PK analysis, a high-quality and high affinity anti Eribulin payload antibody can be used for ADC PK detection and DAR value analysis, which helps evaluate ADC efficacy, assess payload exposure at target sites, and is crucial for providing overall evaluation such as ADC stability.

Q: What is the optimal sample concentration for the Flag-tag Protein Rapid Detection Kit?
A: ≥1 µg/mL.

Q: Do I need controls when using the Flag-tag Protein Rapid Detection Kit?
A: Yes, negative and positive controls must be set up for accurate results. It is recommended that the control samples and the test samples be of the same matrix.

Q: Why does the color intensity of the test line (T) vary after testing different samples?
A: When the sample contains no Flag-tagged protein, the test line (T) shows the darkest color. As the Flag-tagged protein content increases, the color intensity of the test line (T) gradually weakens until it disappears.

Q: Can the Flag-tag Protein Rapid Detection Kit be used for quantitative detection?
A: No. This kit provides qualitative detection of Flag-tagged protein. For quantification, use a relevant quantitative assay kit.

Q: What is the optimal sample concentration for the His-tag Protein Rapid Detection Kit?
A: ≥2 µg/mL.

Q: Do I need controls when using the His-tag Protein Rapid Detection Kit?
A: Yes, negative and positive controls must be set up for accurate results. It is recommended that the control samples and the test samples be of the same matrix.

Q: Why does the color intensity of the test line (T) vary after testing different samples?
A: When the sample contains no His-tagged protein, the test line (T) shows the darkest color. As the His-tagged protein content increases, the color intensity of the test line (T) gradually weakens until it disappears.

Q: Can the His-tag Protein Rapid Detection Kit be used for quantitative detection?
A: No. This kit provides qualitative detection of His-tagged protein. For quantification, use relevant specialized instruments.

Immunoglobulin monomers consist of two heavy chains and two light chains, connected by disulfide bonds. The variable regions of the heavy and light chains together form antigenic determinants. Therefore, the specificity of antibodies is determined by both heavy and light chains. Different subtypes of antibodies have structural differences, and their immunogenicity and in vivo effects vary. Further subdivision and subtype identification of antibodies are of great significance for the study of disease mechanisms and the development of antibody drugs. Among them, light chains are divided into two categories: Kappa and Lambda, with a normal ratio of about 2:1 in the human body. Nearly 40% of light chains in the normal human body are unable to bind with heavy chains every day and are in a free state, known as free light chain (FLC).

FLC is a natural product of B lymphocytes and therefore a unique biomarker for tumors and reactive B cell related diseases. The increase of FLC is associated with malignant plasma imbalance and other lymph node immunoproliferative diseases. Meanwhile, FLC testing is also an important diagnostic aid for various monoclonal globulin diseases. Accurately measuring monoclonal free light chains in serum and urine is particularly important in light chain diseases.

Immunoglobulin monomers consist of two heavy chains and two light chains, connected by disulfide bonds. The variable regions of the heavy and light chains together form antigenic determinants. Therefore, the specificity of antibodies is determined by both heavy and light chains. Different subtypes of antibodies have structural differences, and their immunogenicity and in vivo effects vary. Further subdivision and subtype identification of antibodies are of great significance for the study of disease mechanisms and the development of antibody drugs. Among them, light chains are divided into two categories: Kappa and Lambda, with a normal ratio of about 2:1 in the human body. Nearly 40% of light chains in the normal human body are unable to bind with heavy chains every day and are in a free state, known as free light chain(FLC).

FLC is a natural product of B lymphocytes and therefore a unique biomarker for tumors and reactive B cell related diseases. The increase of FLC is associated with malignant plasma imbalance and other lymph node immunoproliferative diseases. Meanwhile, FLC testing is also an important diagnostic aid for various monoclonal globulin diseases. Accurately measuring monoclonal free light chains in serum and urine is particularly important in light chain diseases.

Streptavidin (SA) is a tetramer protein secreted by Streptomyces during cultivation, with a molecular weight of approximately 65kDa. Streptomycin has similar biological characteristics to avidin, with each subunit possessing a site capable of tightly binding to biotin. It can form stable non covalent specific complexes with the imidazole copper ring of biotin. Streptomycin is often coupled with other active substances such as enzymes, fluorescein, colloidal gold, etc. It can also be coupled with solid-phase carriers such as magnetic beads, microspheres, and microplates to participate in signal amplification in immunology. It is widely used in ELISA, IHC, immunochromatography, protein purification, luminescence diagnosis, biosensors, and the production of biochips.

Immunoglobulin monomers consist of two heavy chains and two light chains, connected by disulfide bonds. The variable regions of the heavy and light chains together form antigenic determinants. Therefore, the specificity of antibodies is determined by both heavy and light chains. Different subtypes of antibodies have structural differences, and their immunogenicity and in vivo effects vary. Further subdivision and subtype identification of antibodies are of great significance for the study of disease mechanisms and the development of antibody drugs. Among them, light chains are divided into two categories: Kappa and Lambda, with a normal ratio of about 2:1 in the human body. Nearly 40% of light chains in the normal human body are unable to bind with heavy chains every day and are in a free state, known as free light chain (FLC).

FLC is a natural product of B lymphocytes and therefore a unique biomarker for tumors and reactive B cell related diseases. The increase of FLC is associated with malignant plasma imbalance and other lymph node immunoproliferative diseases. Meanwhile, FLC testing is also an important diagnostic aid for various monoclonal globulin diseases. Accurately measuring monoclonal free light chains in serum and urine is particularly important in light chain diseases.

Streptavidin (SA) is a tetramer protein secreted by Streptomyces during cultivation, with a molecular weight of approximately 66kDa. Streptomycin has similar biological characteristics to avidin, with each subunit possessing a site capable of tightly binding to biotin. It can form stable non covalent specific complexes with the imidazole copper ring of biotin. Streptomycin is often coupled with other active substances such as enzymes, fluorescein, colloidal gold, etc. It can also be coupled with solid-phase carriers such as magnetic beads, microspheres, and microplates to participate in signal amplification in immunology. It is widely used in ELISA, IHC, immunochromatography, protein purification, luminescence diagnosis, biosensors, and the production of biochips.